WednesdayJan 31, 2024 12:38 pm

Mouse Study Shows Microdoses of Psilocybin Can Combat Anhedonia

Researchers from the University of Southern Denmark have discovered that microdoses of psilocybin, the main psychoactive agent in mushrooms, may be able to alleviate anhedonia. The study used a mouse study to discover that regular small doses of the psychedelic may offer therapeutic benefits against stress-induced anhedonia, a condition that strips individuals of their ability to feel pleasure, and compulsive behavior. Furthermore, psilocybin exhibited therapeutic effectiveness in mice with anhedonia and compulsive behaviors without inducing side effects such as schizophrenia-like symptoms and anxiety. The University of Southern Denmark University team published its findings in the “Molecular Psychiatry” journal. Most of…

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MondayJan 29, 2024 1:21 pm

EU Finances First Psychedelics Research on Incurable Illnesses

The European Union (EU) is funding research into psychedelic-based therapies for patients with incurable diseases. Researchers will use EU funding to determine if psychedelic drugs such as psilocybin can help alleviate psychologic distress in palliative-care patients. While palliative and end-of-life care are designed to relieve physical symptoms and make patients as comfortable as possible, there aren’t a lot of protocols to alleviate the psychological distress that often accompanies incurable illnesses. Psychedelics have exhibited significant potential as mental-health treatments in several initial studies and have shown that they can treat significant mental distress in conditions such as depression and post-traumatic stress…

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FridayJan 26, 2024 12:43 pm

Researchers Gain New Insights into Reports of Mystical Psychedelic Experiences

Researchers from the University of Split’s Medical School’s Department of Medical Humanities recently used computerized linguistic tools to gain insight into online reports of mystical psychedelic experiences. The scientists found that intense psychedelic experiences tend to be accompanied by an increase in negative emotions and mystical language in users. While prior psychedelic-related research typically occurs in clinical settings and leverages structured questionnaires to collect information on mystical psychedelic experiences, the experiences are often limited in depth and nuance. Instead of using questionnaires, the research team analyzed self-reported experiences from actual psychedelic users to obtain new insight into the users’ experiences…

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ThursdayJan 25, 2024 3:15 pm

First Responders, Medical Professionals Implore Nevada Legislators to Reform Psychedelics Laws

Numerous medical professionals and first responders have urged Nevada lawmakers to reform psychedelic laws and allow the use of psychedelics in mental-health treatment. The professionals spoke to a panel of state legislators from the state’s Joint Interim Standing Committee on the Judiciary. Psychedelics have exhibited significant potential as alternative mental-health treatments in recent years, especially against mental disorders such as post-traumatic stress disorder (PTSD) and depression, which often do not respond to conventional treatments. Due to the sometimes traumatic nature of their careers, veterans and first responders often develop conditions such as PTSD and depression after several years on the…

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WednesdayJan 24, 2024 3:04 pm

Nevada Lawmakers Receive Testimonies on Benefits, Concerns Regarding Psychedelics Legalization

A joint legislative committee in the state of Nevada recently heard testimonies on the therapeutic potential of psychedelics. The presentations centered on the impact and science of psychedelic-assisted therapy, with representatives of the Joint Interim Standing Committee focusing on the judiciary also discussing its concerns around psychedelic legalization. The panel was introduced by Senator Rochelle Nguyen, who stated that the presentation’s purpose was to afford the committee an overview of psychedelics. Nguyen sponsored a measure that would establish a state working group to conduct research on psychedelics and come up with plans to permit regulated therapeutic access to the drugs.…

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TuesdayJan 23, 2024 2:28 pm

AlphaFold Uncovers Thousands of Potential Psychedelic Proteins

Researchers recently used an artificial intelligence (AI) tool developed by London-based artificial intelligence research laboratory Deepmind Technologies Limited to identify thousands of potential psychedelic proteins. Called AlphaFold, the artificial intelligence protein-structure prediction tool found hundreds of thousands of new potential psychedelic molecules that could be instrumental in the development of novel antidepressants. The research is a testament to AlphaFold’s ability to easily provide predictions that have applications in everything from experimentally derived protein structure to drug discovery in a fraction of the time such endeavors would have previously taken. AlphaFold’s public database currently has structure predictions for almost every known…

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MondayJan 22, 2024 2:53 pm

New Study Provides Possible Explanation for Antidepression Effects of Psychedelic

A recent study has suggested that psychedelics may deliver their antidepressive effects by “shaking up” the brain networks responsible for regulating emotion. Major advances in psychedelic research have revealed that classic psychedelics have the potential to treat various mental disorders with barely any negative side effects. Researchers have found that psychedelics such as LSD, MDMA and psilocybin can offer long-term relief against a variety of conditions, including  anxiety, depression and post-traumatic stress disorder at relatively low doses. Most of this research is still in its infancy, but the findings are so encouraging that companies are investing tens of millions of…

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FridayJan 19, 2024 3:18 pm

Reintroduced NJ Bill Seeks to Legalize Psilocybin

The state of New Jersey may soon legalize the recreational and therapeutic use of psilocybin mushrooms, following the reintroduction of a measure that was withdrawn in 2023 for revision. The measure, called the Psilocybin Behavioral Health Access and Services Act, concentrates on mental health. Psilocybin is a naturally occurring psychedelic compound found in hallucinogenic mushrooms. According to research, this compound is metabolized in the body to psilocyn and can penetrate the central nervous system. The measure was tabled at the state Senate again last week and has strong support, particularly from Senate President Nick Scutari, who originally sponsored the recreational…

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ThursdayJan 18, 2024 2:34 pm

Addiction to Gambling Could Be Treated Using Psychedelics

Addiction refers to a condition in which an individual is not able to stop engaging in a behavior or using a substance. Gambling addiction is a behavioral addiction that stimulates the reward system of the brain, much as alcohol and drugs do. This addiction is often treated using behavioral therapy, particularly cognitive behavioral therapy, which replaces unhealthy and irrational beliefs with positive, healthy ones. Now, researchers at the Center for Psychedelic Research are using brain imaging to understand behavioral addictions such as gambling and discover new approaches to treat these addictions. They are particularly focused on psychedelic treatments, given the…

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WednesdayJan 17, 2024 3:35 pm

Top 2023 Studies on Ketamine’s Efficacy Against Depression, Mental-Health Illnesses

In the last couple of years, ketamine has been used to treat depression, with ketamine clinics across Canada and the United States administering the drug for the management of anxiety, depression and post-traumatic stress disorder. Ketamine is a dissociative drug commonly used as an anesthetic that causes an individual to lose consciousness and relieve pain. In high doses, ketamine can create neuroplasticity and induce psychedelic experiences. Below, we look at some studies conducted in 2023 that have explored ketamine’s effectiveness in treating a range of mental-health conditions. Ketamine for the prevention of psychiatric disorders induced by stress A study carried…

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