Cybin Inc. (NEO: CYBN) (NYSE American: CYBN) IRB-Approved Study Could ‘Lead to New Frontiers,’ Begins Enrollment This Year

• Upcoming study supports CYBN’s mission to develop psychedelics into therapeutics.
• Kernel Flow uses pulsed light instead of continuous wave light to increase measured brain information. 
• Study may provide crucial “mind-imaging” information that has been previously missing.

Cybin (NEO: CYBN) (NYSE American: CYBN) is starting off the new year right — the company has received approval from an Institutional Review Board (“IRB”) for a feasibility study using Kernel’s quantitative neuroimaging technology, Kernel Flow. Enrollment for the study begins early this year (https://ibn.fm/XTXAe).

“By leveraging the Kernel Flow technology, we may have the ability to measure longitudinal brain activity before, during and after a psychedelic experience, and collect quantitative data as opposed to subjective patient reporting,” said Cybin CEO Doug Drysdale. “We believe the results of this study will lead to future studies that will test the effectiveness of psychedelic treatments and will further support our mission to develop psychedelics into therapeutics.”

The feasibility study is designed to utilize Kernel’s Flow technology to evaluate ketamine’s psychedelic effect on cerebral cortex hemodynamics (https://ibn.fm/YeDwV). This study could provide crucial information that “may lead to new frontiers in psychedelic therapeutics by enabling the acquisition of longitudinal brain activity before, during and after a psychedelic experience, providing quantification of what was previously subjective patient reporting,” the company noted.

“The word psychedelic means ‘mind-manifesting,’ but what has been missing is useful ‘mind-imaging’—the ability to dynamically trace the neural correlates of human conscious experience,” explained Cybin’s chief clinical officer, Dr. Alex Belser. “Conventional neuroimaging just isn’t dynamic enough to study the psychedelic experience in the brain as it happens. This study of ketamine’s psychedelic effects while wearing headgear equipped with sensors to record brain activity could open up new frontiers of understanding.”

Kernel’s exclusive tech, called Kernel Flow, uses pulsed light instead of continuous wave light to increase measured brain information. The device used to measure the information is easily wearable, which is a significant difference from electroencephalography (“EEG”) electrodes that typically require gel on the head or functional magnetic resonance imaging (“fMRI”) studies that require a participant to lie in a scanner. The entire system is the size and look of a bicycle helmet and could, in the future, be more broadly used for neuroscientific or physiological studies of brain activity during psychedelic use, noted Cybin.

“Quantitatively measuring the brain within the context of a psychedelic experience is a promising frontier,” said Kernel founder and CEO Bryan Johnson. “With Kernel Flow, Cybin’s researchers can start putting numbers and quantification to subjective states of mind, including altered ones.”

As a sponsor of the study, Cybin retains an exclusive interest in any innovations that are discovered or developed through its independent analysis of the study findings. Kernel will hold the same rights relating to its Kernel technology.

“We hope this feasibility study can bridge the gap of real-time quantitative data collection during psychedelic treatments to further understand the correlation of effects from these powerful molecules,” said Drysdale. “The ability to access real-time brain activity data during a psychedelic experience has tremendous potential for the development of future psychedelic therapeutics.”

Cybin is a leading ethical biopharmaceutical company, working with a network of world-class partners and internationally recognized scientists, on a mission to create safe and effective therapeutics for patients to address a multitude of mental health issues. Headquartered in Canada and founded in 2019, Cybin is operational in Canada, the United States, the United Kingdom and Ireland. The company is focused on progressing Psychedelics to Therapeutics(TM) by engineering proprietary drug-discovery platforms, innovative drug-delivery systems, novel formulation approaches and treatment regimens for mental health disorders.

For more information, visit the company’s website at www.Cybin.com.

NOTE TO INVESTORS: The latest news and updates relating to CYBN are available in the company’s newsroom at https://ibn.fm/CYBN

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