Researchers Show How Psychedelics Bind to Serotonin Receptors Using Virtual Simulation
Scientists have used virtual reality to demonstrate how a psychedelic compound binds itself to a serotonin receptor. Psychedelics are known to target serotonin receptors, in particular the 5-HT2A receptor. 5-HT2A serotonin receptors are normally found along the central nervous system, particularly in regions of the brain essential for cognition and learning. Several antipsychotics, hallucinogens and antidepressants function by targeting serotonin receptors. Abnormal serotonin receptor activity has been linked to a range of psychiatric conditions and disorders, including schizophrenia, depression and drug addiction. Despite all this knowledge, not much was known about how psychedelic molecules bind themselves to the receptor's structure…