A new study conducted by researchers at the Institute of Psychiatry, Psychology & Neuroscience has found that psilocybin can be administered safely to six participants at the same time, at doses of either 25 mg or 10 mg. Psilocybin is a naturally occurring hallucinogenic compound found in certain mushrooms that grow in Mexico, South America, Europe and the United States.
The research has demonstrated the viability and safety of psilocybin for use in controlled settings in combination with therapy as a possible treatment for various mental health disorders, including post-traumatic stress disorder and treatment-resistant depression. The treatments currently used to manage these conditions are partially or completely ineffective for many individuals, which has resulted in a significant unmet need.
Early studies have shown a potential for psilocybin therapy in treating these individuals. However, no trials have been conducted at the scale required for regulatory approval that will make the therapy available. This study is the first to look into the simultaneous administration of psilocybin.
For their study, the researchers recruited 89 healthy participants who hadn’t used psilocybin in at least 12 months. Of this number, they randomly picked 60 individuals to receive either a 25 mg or 10 mg dose of psilocybin. The remaining 29 were the control group and were administered with a placebo. All the participants received support from trained psychotherapists after the drug/placebo was administered.
The researchers closely monitored the participants who had received psilocybin for six to eight hours before following up with them for 12 weeks. During this period, the researchers evaluated the participants for potential changes, including sustained planning, memory and attention as well as their ability to process their emotions. The researchers recorded no instances of participants withdrawing from the trial because of the occurrence of an adverse event, noting that they also observed no consistent trends suggesting that either of the psilocybin doses administered had detrimental effects on participants.
Lead author of the study Dr. James Rucker stated that the research was an important demonstration that the administration of psilocybin could be further explored, noting that demonstrating the safety and feasibility of administering the drug to more than one individual simultaneously could help find ways to scale up the treatment. Rucker is a research clinical scientist at the National Institute for Health as well as an honorary consultant psychiatrist at Maudsley NHS Foundation Trust. The study was carried out in partnership with Compass Pathways and its findings were published in the “Journal of Psychopharmacology.”
With the high rate at which science-based support for the therapeutic use of psychedelics is accumulating, it may not be long before various remedies developed by sector players such as Delic Holdings Corp. (CSE: DELC) (OTCQB: DELCF) are readily available wherever patients need them.
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